Structural and functional brain changes in bipolar disorder: a selective review.

@article{Pearlson1999StructuralAF,
  title={Structural and functional brain changes in bipolar disorder: a selective review.},
  author={Godfrey D. Pearlson},
  journal={Schizophrenia research},
  year={1999},
  volume={39 2},
  pages={133-40; discussion 162}
}
The purpose of this paper is to provide a concise, selective review of the major issues and findings germane to structural and functional neuroimaging studies of bipolar affective disorder (BPD). In attempting to identify the brain changes associated with BPD, investigators have used neuroimaging techniques to focus on several interrelated questions. These are: What are the changes and where do they occur? Do their nature and location suggest a particular etiopathologic basis or have notable… CONTINUE READING