Structural and functional association of Trypanosoma brucei MIX protein with cytochrome c oxidase complex.

@article{Zkov2008StructuralAF,
  title={Structural and functional association of Trypanosoma brucei MIX protein with cytochrome c oxidase complex.},
  author={Alena Z{\'i}kov{\'a} and Aswini Kumar Panigrahi and Alessandro D. Uboldi and Rachel A. Dalley and Emanuela Handman and Kenneth D. Stuart},
  journal={Eukaryotic cell},
  year={2008},
  volume={7 11},
  pages={
          1994-2003
        }
}
A mitochondrial inner membrane protein, designated MIX, seems to be essential for cell viability. The deletion of both alleles was not possible, and the deletion of a single allele led to a loss of virulence and aberrant mitochondrial segregation and cell division in Leishmania major. However, the mechanism by which MIX exerts its effect has not been determined. We show here that MIX is also expressed in the mitochondrion of Trypanosoma brucei, and using RNA interference, we found that its loss… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 42 REFERENCES

Similar Papers

Loading similar papers…