Structural and functional analysis of the β-barrel domain of BamA from Escherichia coli.

Abstract

In gram-negative bacteria, the assembly of outer membrane proteins (OMPs) requires a β-barrel assembly machinery (BAM) complex, of which BamA is an essential and evolutionarily conserved component. To elucidate the mechanism of BamA-mediated OMP biogenesis, we determined the crystal structure of the C-terminal transmembrane domain of BamA from Escherichia… (More)
DOI: 10.1096/fj.13-248450

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