Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA

@inproceedings{Wojtas2012StructuralAF,
  title={Structural and functional analyses of the interaction of archaeal RNA polymerase with DNA},
  author={Magdalena N. Wojtas and Maria Mogni and Oscar Millet and Stephen D Bell and Nicola G. A. Abrescia},
  booktitle={Nucleic acids research},
  year={2012}
}
Multi-subunit RNA polymerases (RNAPs) in all three domains of life share a common ancestry. The composition of the archaeal RNAP (aRNAP) is not identical between phyla and species, with subunits Rpo8 and Rpo13 found in restricted subsets of archaea. While Rpo8 has an ortholog, Rpb8, in the nuclear eukaryal RNAPs, Rpo13 lacks clear eukaryal orthologs. Here, we report crystal structures of the DNA-bound and free form of the aRNAP from Sulfolobus shibatae. Together with biochemical and biophysical… CONTINUE READING
Highly Cited
This paper has 17 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
9 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Similar Papers

Loading similar papers…