Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension.

@article{Schwartzkopff1993StructuralAF,
  title={Structural and functional alterations of the intramyocardial coronary arterioles in patients with arterial hypertension.},
  author={Bodo Schwartzkopff and Wolfgang Motz and Hartmut Frenzel and Manfred Vogt and Sabine Knauer and Bodo Eckehard Strauer},
  journal={Circulation},
  year={1993},
  volume={88 3},
  pages={993-1003}
}
BACKGROUND In hypertensive patients with angina pectoris, the coronary vasodilator reserve is frequently impaired despite a normal coronary angiogram. Experimental data indicate that structural alterations of the intramyocardial coronary vasculature contribute to an increased minimal coronary resistance and a diminished coronary flow reserve. METHODS AND RESULTS In 14 patients (10 men and 4 women) with arterial hypertension and 8 normotensive subjects, minimal coronary resistance and… CONTINUE READING

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