Structural and functional MRIs disclose cerebellar pathologies in idiopathic downbeat nystagmus.

@article{Hfner2007StructuralAF,
  title={Structural and functional MRIs disclose cerebellar pathologies in idiopathic downbeat nystagmus.},
  author={Katharina H{\"u}fner and Th Stephan and Roger Kalla and Angela Deutschl{\"a}nder and Janelle Wagner and M Holtmannsp{\"o}tter and Gernot Schulte-Altedorneburg and Michael Strupp and Thomas W. Brandt and Stefan Glasauer},
  journal={Neurology},
  year={2007},
  volume={69 11},
  pages={
          1128-35
        }
}
BACKGROUND Neurologic disorders in which the etiology and pathogenesis are not yet understood are termed idiopathic. Downbeat nystagmus (DBN) is a frequent eye movement disorder that clinically manifests with oscillopsia and postural instability. Forty percent of patients with DBN are classified as having idiopathic DBN, because no underlying pathology can be demonstrated by conventional MRI or laboratory tests. METHODS We evaluated gray matter brain volumes of 11 patients with idiopathic DBN… CONTINUE READING
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