Structural and Mechanistic Insight into DNA Unwinding by Deinococcus radiodurans UvrD

Abstract

DNA helicases are responsible for unwinding the duplex DNA, a key step in many biological processes. UvrD is a DNA helicase involved in several DNA repair pathways. We report here crystal structures of Deinococcus radiodurans UvrD (drUvrD) in complex with DNA in different nucleotide-free and bound states. These structures provide us with three distinct… (More)
DOI: 10.1371/journal.pone.0077364

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@inproceedings{Stelter2013StructuralAM, title={Structural and Mechanistic Insight into DNA Unwinding by Deinococcus radiodurans UvrD}, author={Meike Stelter and Samira Acajjaoui and Se{\'a}n M. McSweeney and Joanna Timmins}, booktitle={PloS one}, year={2013} }