Structural and Mechanical Improvements to Bone Are Strain Dependent with Axial Compression of the Tibia in Female C57BL/6 Mice

@inproceedings{Berman2015StructuralAM,
  title={Structural and Mechanical Improvements to Bone Are Strain Dependent with Axial Compression of the Tibia in Female C57BL/6 Mice},
  author={Alycia G. Berman and Creasy A. Clauser and Caitlin Wunderlin and Max A. Hammond and Joseph M Wallace and Deepak Vashishth},
  booktitle={PloS one},
  year={2015}
}
Strain-induced adaption of bone has been well-studied in an axial loading model of the mouse tibia. However, most outcomes of these studies are restricted to changes in bone architecture and do not explore the mechanical implications of those changes. Herein, we studied both the mechanical and morphological adaptions of bone to three strain levels using a targeted tibial loading mouse model. We hypothesized that loading would increase bone architecture and improve cortical mechanical properties… CONTINUE READING
3 Citations
40 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Exercise prevents Beta-aminopropionitrile induced morphological changes to Type I collagen in Murine Bone

  • HammondMA, JM Wallace
  • BoneKEy Reports
  • 2015

Similar Papers

Loading similar papers…