Structural and Genetic Characterization of Enterohemorrhagic Escherichia coli O145 O Antigen and Development of an O145 Serogroup-Specific PCR Assay

@article{Feng2005StructuralAG,
  title={Structural and Genetic Characterization of Enterohemorrhagic Escherichia coli O145 O Antigen and Development of an O145 Serogroup-Specific PCR Assay},
  author={Lu Feng and S. Senchenkova and J. Tao and A. Shashkov and B. Liu and S. Shevelev and P. Reeves and Jianguo Xu and Y. Knirel and L. Wang},
  journal={Journal of Bacteriology},
  year={2005},
  volume={187},
  pages={758 - 764}
}
ABSTRACT Enterohemorrhagic Escherichia coli O145 strains are emerging as causes of hemorrhagic colitis and hemolytic uremic syndrome. In this study, we present the structure of the E. coli O145 O antigen and the sequence of its gene cluster. The O145 antigen has repeat units containing three monosaccharide residues: 2-acetamido-2-deoxy-d-glucose (GlcNAc), 2-acetamidoylamino-2,6-dideoxy-l-galactose, and N-acetylneuraminic acid. It is very closely related to Salmonella enterica serovar Touera and… Expand
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