Structural and Functional Peculiarities of Homologous Domains of Angiotensin-Converting Enzyme


Somatic angiotensin-converting enzyme (ACE) consists of two homologous domains, each of them containing an active site. Differences in substrate specificities and affinity to inhibitors of the active sites of the two domains of bovine ACE are described. The ACE domains demonstrate different thermostability, and the reasons for this difference are analyzed… (More)
DOI: 10.1023/A:1026045324442


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