Structural and Functional Characterization of Disulfide Isoforms of the Human IgG 2 Subclass *

@inproceedings{Dillon2008StructuralAF,
  title={Structural and Functional Characterization of Disulfide Isoforms of the Human IgG 2 Subclass *},
  author={Thomas M. Dillon and Margaret Speed Ricci and Chris Vezina and Gregory C. Flynn and Yaoqing Diana Liu and Douglas S. Rehder and Matthew H Plant and Brad Henkle and Yu Li and Songpon Deechongkit and Brian Varnum and Jette Wypych and Alain Balland and Pavel V. Bondarenko},
  year={2008}
}
In the accompanying report (Wypych, J., Li, M., Guo, A., Zhang, Z., Martinez, T., Allen, M. J., Fodor, S., Kelner, D. N., Flynn, G. C., Liu, Y. D., Bondarenko, P. V., Ricci, M. S., Dillon, T. M., and Balland, A. (2008) J. Biol. Chem. 283, 16194–16205), we have identified that the human IgG2 subclass exists as an ensemble of distinct isoforms, designated IgG2-A, -B, and -A/B, which differ by the disulfide connectivity at the hinge region. In this report, we studied the structural and functional… CONTINUE READING