Structural analysis of point mutations in the Hairless gene and their association with the activity of the Hairless protein.

Abstract

The Notch signaling pathway (NSP) is an important intercellular communication mechanism that regulates embryo development and adult physiological functions. The Hairless (H) protein is a powerful antagonist of the NSP by its interaction with the Suppressor of Hairless (Su[H]) protein, recruiting the corepressors Gro and CtBP. In the present work, we… (More)
DOI: 10.1016/j.ijbiomac.2008.08.012

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Cite this paper

@article{PazGmez2008StructuralAO, title={Structural analysis of point mutations in the Hairless gene and their association with the activity of the Hairless protein.}, author={Daniel Paz-G{\'o}mez and V{\'i}ctor M Baizabal-Aguirre and Juan Jos{\'e} Valdez-Alarc{\'o}n and Marcos Cajero-Ju{\'a}rez and Anja C. Nagel and Anette Preiss and Dieter Maier and Alejandro Bravo-Pati{\~n}o}, journal={International journal of biological macromolecules}, year={2008}, volume={43 5}, pages={426-32} }