Structural analysis of flagellar axonemes from inner arm dynein knockdown strains of Trypanosoma brucei.

@article{Zukas2012StructuralAO,
  title={Structural analysis of flagellar axonemes from inner arm dynein knockdown strains of Trypanosoma brucei.},
  author={Randi Zukas and Alex J. Chang and Marian C. Rice and Amy L. Springer},
  journal={Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al},
  year={2012},
  volume={36 3},
  pages={
          133-41
        }
}
Trypanosoma brucei is a protozoan flagellate that causes African sleeping sickness. Flagellar function in this organism is critical for life cycle progression and pathogenesis, however the regulation of flagellar motility is not well understood. The flagellar axoneme produces a complex beat through the precisely coordinated firing of many proteins, including multiple dynein motors. These motors are found in the inner arm and outer arm complexes. We are studying one of the inner arm dynein… CONTINUE READING

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