Structural analysis of antiviral sulfated alpha-D-(1-->3)-linked mannans.


The structures of two alpha-(1-->3)-alpha-D-xylo-mannans were determined. The different antiviral activity of the xylo-mannans from Nothogenia fastigiata was explained on the basis of a flexible backbone, molecular size, content and distribution of sulfate groups and of the single stubs of beta-(1-->2)-linked D-xylose. 


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