Structural analysis of MHC alleles in an RSV tumour regression chicken using a BAC library.

@article{Suzuki2012StructuralAO,
  title={Structural analysis of MHC alleles in an RSV tumour regression chicken using a BAC library.},
  author={Kensuke Suzuki and Eiji Kobayashi and Hitomi Kobayashi Yamashita and Hirohide Uenishi and I. V. Churkina and Graham Plastow and Noriyuki Hamasima and Tadayoshi Mitsuhashi},
  journal={Animal genetics},
  year={2012},
  volume={43 3},
  pages={348-51}
}
The chicken major histocompatibility complex (MHC-B locus) has a strong association with resistance and susceptibility to numerous diseases. We have found a B haplotype designated WLA that associated with the regression of tumours caused by Rous sarcoma virus J strain (RSV-J). Haplotype WLA was identical to the regressive B6 haplotype when partial genotyping was performed (Poultry Science, 89, 2010, 651). We then constructed a bacterial artificial chromosome (BAC) library from a WLA homozygote… CONTINUE READING