Structural alignment of proteins by a novel TOPOFIT method, as a superimposition of common volumes at a topomax point.

@article{Ilyin2004StructuralAO,
  title={Structural alignment of proteins by a novel TOPOFIT method, as a superimposition of common volumes at a topomax point.},
  author={Valentin A. Ilyin and Alexej Abyzov and Chesley M. Leslin},
  journal={Protein science : a publication of the Protein Society},
  year={2004},
  volume={13 7},
  pages={1865-74}
}
Similarity of protein structures has been analyzed using three-dimensional Delaunay triangulation patterns derived from the backbone representation. It has been found that structurally related proteins have a common spatial invariant part, a set of tetrahedrons, mathematically described as a common spatial subgraph volume of the three-dimensional contact graph derived from Delaunay tessellation (DT). Based on this property of protein structures, we present a novel common volume superimposition… CONTINUE READING