Structural adaptation of vascular networks: role of the pressure response.

@article{Pries2001StructuralAO,
  title={Structural adaptation of vascular networks: role of the pressure response.},
  author={Axel Radlach Pries and Bettina Reglin and Timothy W. Secomb},
  journal={Hypertension},
  year={2001},
  volume={38 6},
  pages={1476-9}
}
Structural reductions in vessel luminal diameters in response to elevated pressure may play a role in the elevation of peripheral resistance generally observed in hypertension. In the present study, a theoretical model is used to simulate the effect of increased driving pressure on flow resistance in microvascular networks. The angioarchitecture (lengths and diameters of all segments, topology) of microvascular networks (n=6) in the rat mesentery was recorded by intravital microscopy. The model… CONTINUE READING
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