Structural abnormalities of chromosome 7q in chronic lymphoproliferative disorders.

@article{Oscier1996StructuralAO,
  title={Structural abnormalities of chromosome 7q in chronic lymphoproliferative disorders.},
  author={David Oscier and Anne C Gardiner and Sarah Mould},
  journal={Cancer genetics and cytogenetics},
  year={1996},
  volume={92 1},
  pages={24-7}
}
Structural abnormalities of 7q are common in myeloid malignancies but rarely reported in chronic lymphoproliferative disorders. 7q abnormalities were found in 29 of 796 patients (3.6%) with chronic lymphoid malignancies. The most common association was found in splenic lymphoma with villous lymphocytes (SLVL) in which 8 of 31 cases (26%) has one or more abnormalities of 7q. The most common abnormalities were deletions involving 7q32 and deletions or translocation of 7q22. There was no… CONTINUE READING