Structural Study of Methylated and Non-Methylated Duplexes by IR Fourier Spectroscopy

@inproceedings{Kunitsyn2015StructuralSO,
  title={Structural Study of Methylated and Non-Methylated Duplexes by IR Fourier Spectroscopy},
  author={Valery Georgievich Kunitsyn and Pavel A. Kuznetsov and E. N. Demchenko and O. I. Gimautdinova},
  year={2015}
}
Structure of the duplex consisting of 23 pairs of bases was studied before and after the methylation of two cytosine molecules from different chains of the duplex. The study was performed in a buffer solution using an IR Fourier spectrometer. The absorption bands corresponding to the duplex backbone were found to change their characteristics after the methylation. Firstly, the integrated intensity ratio of the absorption bands, S1044/S1085, decreased by a factor of 1.5. The absorption band at… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 15 REFERENCES

Structural and Functional Features of the 5-Methylcytosine Distribution in the Eukaryotic Genome

O. V. Dyachenko, T. V. Shevchyk, Y. I. Buryanov
  • Molecular Biology,
  • 2010
VIEW 1 EXCERPT