Structural Insights into Rotavirus Entry.

  title={Structural Insights into Rotavirus Entry.},
  author={Javier M Rodr{\'i}guez and Daniel Luque},
  journal={Advances in experimental medicine and biology},
To initiate infection, non-enveloped viruses must recognize a target cell and penetrate the cell membrane by pore formation or membrane lysis. Rotaviruses are non-enveloped dsRNA viruses that infect the mature intestinal epithelium. They are major etiologic agents of diarrheal disease in human infants, as well as in young individuals of various avian and mammalian species. Rotavirus entry into the cell is a complex multistep process initiated by the interaction of the tip of the viral spike… 

Rotavirus cell entry: not so simple after all.

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Penetration of non-enveloped viruses.



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