Structural Insights into Genetic Variants of Na+/Glucose Cotransporter SGLT1 Causing Glucose–Galactose Malabsorption: vSGLT as a Model Structure

@article{Raja2012StructuralII,
  title={Structural Insights into Genetic Variants of Na+/Glucose Cotransporter SGLT1 Causing Glucose–Galactose Malabsorption: vSGLT as a Model Structure},
  author={M Mobeen Raja and Rolf K.-H. Kinne},
  journal={Cell Biochemistry and Biophysics},
  year={2012},
  volume={63},
  pages={151-158}
}
Current advances in structural biology provide valuable insights into structure–function relationship of membrane transporters by solving crystal structures of bacterial homologs of human transporters. Therefore, scientists consider bacterial transporters as useful structural models for designing of drugs targeted in human diseases. The functional homology… CONTINUE READING