Structural Insights for Drugs Developed for Phospholipase D Enzymes.

Abstract

BACKGROUND In recent years human phospholipase D enzymes (PLD1 and PLD2 isozymes) have emerged as drug targets for various diseases such as cardiovascular disease, cancer, infectious diseases and neurodegenerative conditions such as Alzheimer's and Parkinson's disease. The interest in PLD as a drug target is due to the fact that PLD enzymes belong to a… (More)
DOI: 10.2174/1570163814666170816112135

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