Structural Insight into the Rotational Switching Mechanism of the Bacterial Flagellar Motor

Abstract

The bacterial flagellar motor can rotate either clockwise (CW) or counterclockwise (CCW). Three flagellar proteins, FliG, FliM, and FliN, are required for rapid switching between the CW and CCW directions. Switching is achieved by a conformational change in FliG induced by the binding of a chemotaxis signaling protein, phospho-CheY, to FliM and FliN. FliG… (More)
DOI: 10.1371/journal.pbio.1000616

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