Structural Effects of Sulconazole Nitrate on the Hyphal Growth of Trichophyton rubrum

@article{Taki1991StructuralEO,
  title={Structural Effects of Sulconazole Nitrate on the Hyphal Growth of Trichophyton rubrum},
  author={Akiko Taki and Naoko Yamada and Katsuhisa Uchida and Hideyo Yamaguchi and Masako Osumi},
  journal={Nippon Ishinkin Gakkai Zasshi},
  year={1991},
  volume={32},
  pages={31-42}
}
2 Citations
Novel in vivo observations on double acting points of luliconazole on Trichophyton rubrum: an ultrastructural study.
TLDR
It is hypothesized that luliconazole has double acting points, on the plasma membrane and cell wall, of dermatophyte hyphae, as well as cell wall alterations with initial development of and accumulation of a granular structure in the outermost layer and subsequent amorphous and electron-lucent change of the thickened inner part of the cell wall.

References

SHOWING 1-6 OF 6 REFERENCES
Minimal antibiotic concentrations of aminoglycosides and beta-lactam antibiotics for some gram-negative bacilli and gram-positive cocci.
The minimal antibiotic concentration (MAC) is the lowest concentration of an antibacterial agent that produces a decrease of 1 log in the number of organisms/ml as compared with a control culture in
The effect of bifonazole on the structure of Trichophyton mentagrophytes.
TLDR
The results strongly suggest that subinhibitory concentrations of bifonazole profoundly affected the normal growth and induced degenerative changes of the hyphae of T. mentagrophytes probably by affecting some essential metabolism or structure of the fungal cell.
Microscopic studies of Candida albicans and Torulopsis glabrata after in vitro treatment with bifonazole. Light and scanning electron microscopy.
TLDR
Evidence is presented by means of fluorescence microscopy that bifonazole-treated yeast cells of C. albicans frequently lacked septa and often contained irregular deposition of chitin.
Microscopic studies of Candida albicans and Torulopsis glabrata after in vitro treatment with bifonazole. Freeze fracture electron microscopy.
1-[(4-Biphenylyl)-phenylmethyl]-1H-imidazole (bifonazole, Bay h 4502, Mycospor) induced profound ultrastructural alterations in Candida albicans and Torulopsis glabrata as observed by freeze fracture
Reversed-phase high-pressure liquid chromatographic analysis of sulconazole in plasma.
TLDR
A sensitive and specific analytical method for the measurement of sulconazole in plasma is described, which can be measured with confidence with confidence over the concentration range of 0.5-5 microgram/ml for sul Conazole from dog plasma.