Structural Determinants of Water Permeability through the Lipid Membrane

@article{Mathai2008StructuralDO,
  title={Structural Determinants of Water Permeability through the Lipid Membrane},
  author={John C. Mathai and Stephanie Tristram-Nagle and John F. Nagle and Mark Lawrence Zeidel},
  journal={The Journal of General Physiology},
  year={2008},
  volume={131},
  pages={69 - 76}
}
Despite intense study over many years, the mechanisms by which water and small nonelectrolytes cross lipid bilayers remain unclear. While prior studies of permeability through membranes have focused on solute characteristics, such as size, polarity, and partition coefficient in hydrophobic solvent, we focus here on water permeability in seven single component bilayers composed of different lipids, five with phosphatidylcholine headgroups and different chain lengths and unsaturation, one with a… CONTINUE READING
Highly Cited
This paper has 91 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

92 Citations

01020'10'12'14'16'18
Citations per Year
Semantic Scholar estimates that this publication has 92 citations based on the available data.

See our FAQ for additional information.

References

Publications referenced by this paper.
Showing 1-10 of 25 references

Structure and fl uctuations of charged phosphatidylserine bilayers in the absence of salt

  • K. C. Olbrich, T. McIntosh, D. Needham, E. Evans
  • Biophys . J .
  • 2004