Structural Characterization of Chlorophyll-a by High Resolution Tandem Mass Spectrometry

@article{Wei2013StructuralCO,
  title={Structural Characterization of Chlorophyll-a by High Resolution Tandem Mass Spectrometry},
  author={Juan Wei and Huilin Li and Mark P. Barrow and Peter B. O’Connor},
  journal={Journal of The American Society for Mass Spectrometry},
  year={2013},
  volume={24},
  pages={753-760}
}
AbstractA high resolution Fourier transform ion cyclotron resonance (FTICR) mass spectrometer is used for characterizing the fragmentation of chlorophyll-a. Three tandem mass spectrometry (MS/MS) techniques, including electron-induced dissociation (EID), collisionally activated dissociation (CAD), and infrared mutiphoton dissociation (IRMPD) are applied to the singly protonated chlorophyll-a. Some previously unpublished fragments are identified unambiguously by utilizing high resolution and… Expand
Extensive fragmentation of pheophytin-a by infrared multiphoton dissociation tandem mass spectrometry.
TLDR
The detection of odd-electron fragments in the CID and IRMPD spectra of protonated pheophytin-a suggests that the macrocyclic structure effectively stabilizes radicals, and these radical ions seem to have a relatively higher abundance in the presence of the central Mg atom. Expand
Improvement of chlorophyll identification in foodstuffs by MALDI ToF/ToF mass spectrometry using 1,5-diaminonaphthalene electron transfer secondary reaction matrix
TLDR
DAN was proved to drastically outperform conventional matrices such as α-cyano-4-hydroxycinnnamic acid, dithranol, antracene, and even terthiophene, and the potential of MALDI MS to detect illegal vegetable oil re-greening practices is shown. Expand
Structural analysis of small to medium-sized molecules by mass spectrometry after electron-ion fragmentation (ExD) reactions.
TLDR
The application of ExD to small and medium-sized molecules is described and important applications to natural products, biomedical compounds, synthetic molecules, crude oils, and environmental toxins are reviewed. Expand
Characterisation of phosphorylated nucleotides by collisional and electron‐based tandem mass spectrometry
TLDR
The presence of sodium in a precursor ion directs electron‐induced bond dissociation, thus enabling targeted, and therefore tuneable, fragmentation of groups within that precursor ion. Expand
Structural Characterization of Intact Glycoconjugates by Tandem Mass Spectrometry Using Electron-Induced Dissociation.
TLDR
EID is not only a complementary method to CID, but also a method that can generate extensive fragment ions for the structural characterization of all intact glycoconjugates studied and isomeric ganglioside species can be differentiated. Expand
Combining Ultraviolet Photodissociation and Two-Dimensional Mass Spectrometry: A Contemporary Approach for Characterizing Singly Charged Agrochemicals.
TLDR
The performance of the 193 nm UVPD fragmentation technique on structural/moiety characterization of 14 singly charged agrochemicals is demonstrated, demonstrating that UVPD is viable for these types of species. Expand
Fragmentation patterns of boron-dipyrromethene (BODIPY) dyes by electrospray ionization high-resolution tandem mass spectrometry.
TLDR
Detailed dissociation mechanisms were proposed in this study for BODIPY dyes and the elemental formulae of CID product ions were unambiguously assigned using FTICR-MS and unique fragment ions were discovered for the rapid identification of methyl, ethyl, butyl, tert-butyl, and phenyl substituents of individual dyes in B ODIPY synthesis mixtures by low-resolution MS. Expand
Comparison of Fragmentation Techniques for the Structural Characterisation of Singly Charged Agrochemicals.
TLDR
The results obtained displayed many more cross-ring fragmentation of the pyrimidine ring compared to the pyridine ring, highlighting the potential for HRAM MS and EID to be used as a tool for structural characterisation of small molecules with a wide variety of functional groups and structural motifs. Expand
The Advantages of Two-Dimensional Electron-Induced Dissociation and Infrared Multiphoton Dissociation Mass Spectrometry for the Analysis of Agrochemicals.
TLDR
A 2DMS technique on a 12 T Fourier transform ion cyclotron resonance mass spectrometer (FT-ICR MS) that can analyze a mixture of agrochemicals without using chromatography or quadrupole isolation in a single experiment is demonstrated. Expand
Advanced applications of high performance Fourier transform ion cyclotron resonance mass spectrometry
Fourier transform ion cyclotron resonance mass spectrometry (FTICR MS) displays its advances in obtaining high resolving power, high mass accuracy, and coupling with many different tandem massExpand
...
1
2
3
4
...

References

SHOWING 1-10 OF 44 REFERENCES
Determination of structure and properties of modified chlorophylls by using fast atom bombardment combined with tandem mass spectrometry
TLDR
Tandem mass spectrometry was used to investigate and compare the decompositions of radical cations, radical anions, and [M + Cat]+ ions of chlorophylls and found fragment ions that are complementary to those of the M+ and are used to examine the intrinsic gas-phase reactivity of metal ions and chlorophyLLs. Expand
Structural characterization of polyketides using high mass accuracy tandem mass spectrometry.
TLDR
Combining CAD and EID for the structural characterization of polyketide characterization will be a useful tool for identifying and characterizing unknown polyketides and their biosynthetic intermediates. Expand
Structural study of spirolide marine toxins by mass spectrometry
TLDR
This study has focused on mass spectrometric characterization of the main component of this extract, 13-desmethyl spirolide C, and proposed a fragmentation scheme for this toxin to explain the formation of the collision-induced fragments. Expand
Investigation of porphyrins and metalloporphyrins using two-step laser mass spectrometry.
TLDR
Laser desorption time-of-flight mass spectrometry with laser postionization at 193 nm has been used to study a series of selected porphyrin and metalloporphyrins, suggesting that information concerning the interaction between adsorbate and substrate can be extracted. Expand
High-energy fragmentation of chlorophyll a and its fully deuterated analogue by /sup 252/Cf plasma desorption mass spectrometry
Comparison of the /sup 252/Cf=plasma distortion mass spectrometry (/sup 252/Cf-POMS) spectra of chlorophyll of ordinary isotopic composition((/sup 1/H)Chl a) with those of essentially fullyExpand
Analysis of chlorophylls and their derivatives by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry.
TLDR
The analysis of chlorophylls and their derivatives by matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry is described and terthiophene was the most efficient without releasing metal ions, although it caused fragmentation of the phytol-ester linkage. Expand
252Cf Fission Fragment Ionization Mass Spectrometry of Chlorophyll a
The title study has been made by using a time-of-flight mass spectrometer, placing primary emphasis on fragmentation reactions and rates. The mass spectrometer was modified so that segmented fieldsExpand
Electron-induced dissociation of glycosaminoglycan tetrasaccharides
TLDR
This work performs electron-induced dissociation (EID) on singly charged GAGs to identify products that form via direct decomposition by eliminating the pathway of electron detachment, and suggests that for EDD, electron detachment plays a significant role in distinguishing glucuronic acid from iduronic Acid. Expand
Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process
Neutralization-reionization mass spectrometry (MS)1 is of unique value for preparing and characterizing highly reactive and unstable neutral species, such as the intermediate in theExpand
Porphyrin Pyrrole Sequencing: Low-Energy Collision-Induced Dissociation of (M + 7H)+ Generated in Situ during Ammonia Chemical Ionization
A method for pyrrole sequencing of porphyrins, based on high-pressure ammonia chemical ionization mass spectrometry/mass spectrometry (CI-MS/MS), is presented. High-pressure ammonia CI of porphyrinsExpand
...
1
2
3
4
5
...