Structural Characterization And Therapeutic Utility Of The Proton-Coupled Folate Transporter

@inproceedings{Wilson2016StructuralCA,
  title={Structural Characterization And Therapeutic Utility Of The Proton-Coupled Folate Transporter},
  author={Michael R Wilson},
  year={2016}
}
STRUCTURAL CHARACTERIZATION AND THERAPEUTIC UTILITY OF THE PROTON-COUPLED FOLATE TRANSPORTER by MICHAEL ROY WILSON December 2016 Advisor: Dr. Larry H. Matherly Major: Cancer Biology Degree: Doctor of Philosophy Folate is a B9 vitamin essential to DNA synthesis. The proton-coupled folate transporter (PCFT) is a newly discovered proton/folate symporter with an acidic pH optimum and broad expression across a variety of solid tumor types, with limited expression in normal tissues. Several… CONTINUE READING

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