Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations.

@article{Putzu2017StructuralBO,
  title={Structural Behavior of the Peptaibol Harzianin HK VI in a DMPC Bilayer: Insights from MD Simulations.},
  author={Marina Putzu and Sezgin Kara and Sergii Afonin and Stephan L. Grage and Andrea Bordessa and Gr{\'e}gory Chaume and Thierry Brigaud and Anne S Ulrich and Tom{\'a}{\vs} Kubař},
  journal={Biophysical journal},
  year={2017},
  volume={112 12},
  pages={
          2602-2614
        }
}
Microsecond molecular dynamics simulations of harzianin HK VI (HZ) interacting with a dimyristoylphosphatidylcholine bilayer were performed at the condition of low peptide-to-lipid ratio. Two orientations of HZ molecule in the bilayer were found and characterized. In the orientation perpendicular to the bilayer surface, HZ induces a local thinning of the bilayer. When inserted into the bilayer parallel to its surface, HZ is located nearly completely within the hydrophobic region of the bilayer… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
1 Extracted Citations
94 Extracted References
Similar Papers

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 94 references

Helical structures of homochiral isotope-labeled a-aminoisobutyric acid peptides

  • A. Ueda, M. Oba, M. Tanaka
  • 2016

Similar Papers

Loading similar papers…