Structural Basis of Response Regulator Inhibition by a Bacterial Anti-Activator Protein

@inproceedings{Baker2011StructuralBO,
  title={Structural Basis of Response Regulator Inhibition by a Bacterial Anti-Activator Protein},
  author={Melinda D. Baker and Matthew B. Neiditch},
  booktitle={PLoS biology},
  year={2011}
}
The complex interplay between the response regulator ComA, the anti-activator RapF, and the signaling peptide PhrF controls competence development in Bacillus subtilis. More specifically, ComA drives the expression of genetic competence genes, while RapF inhibits the interaction of ComA with its target promoters. The signaling peptide PhrF accumulates at high cell density and upregulates genetic competence by antagonizing the interaction of RapF and ComA. How RapF functions mechanistically to… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
22 Citations
70 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 70 references

Sequencing of plasmids from a multi-antimicrobial resistant Salmonella enterica serovar Dublin strain

  • J Han, AM Lynne, DE David, R Nayak, SL Foley
  • Food Res Int;doi: 10.1016/j.foodres.2011.1004…
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…