Structural Basis for Heavy Metal Detoxification by an Atm1-Type ABC Exporter

@article{Lee2014StructuralBF,
  title={Structural Basis for Heavy Metal Detoxification by an Atm1-Type ABC Exporter},
  author={Jonas Y. Lee and Janet G. Yang and Daniel Zhitnitsky and Oded Lewinson and Douglas C Rees},
  journal={Science},
  year={2014},
  volume={343},
  pages={1133-1136}
}
Although substantial progress has been achieved in the structural analysis of exporters from the superfamily of adenosine triphosphate (ATP)–binding cassette (ABC) transporters, much less is known about how they selectively recognize substrates and how substrate binding is coupled to ATP hydrolysis. We have addressed these questions through crystallographic analysis of the Atm1/ABCB7/HMT1/ABCB6 ortholog from Novosphingobium aromaticivorans DSM 12444, NaAtm1, at 2.4 angstrom resolution… CONTINUE READING
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Biochim

  • A. Zutz, S. Gompf, H. Schägger, R. Tampé
  • Biophys. Acta
  • 1787

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