Structural Analysis of the Roles of Influenza A Virus Membrane-Associated Proteins in Assembly and Morphology.

@article{Chlanda2015StructuralAO,
  title={Structural Analysis of the Roles of Influenza A Virus Membrane-Associated Proteins in Assembly and Morphology.},
  author={Petr Chlanda and Oliver Schraidt and Susann Kummer and James D. Riches and Heike Oberwinkler and Simone Prinz and Hans-Georg Kr{\"a}usslich and John A. G. Briggs},
  journal={Journal of virology},
  year={2015},
  volume={89 17},
  pages={8957-66}
}
UNLABELLED The assembly of influenza A virus at the plasma membrane of infected cells leads to release of enveloped virions that are typically round in tissue culture-adapted strains but filamentous in strains isolated from patients. The viral proteins hemagglutinin (HA), neuraminidase (NA), matrix protein 1 (M1), and M2 ion channel all contribute to virus assembly. When expressed individually or in combination in cells, they can all, under certain conditions, mediate release of membrane… CONTINUE READING
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