Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36.

@article{Greenwalt1990StructuralFA,
  title={Structural, functional, and antigenic differences between bovine heart endothelial CD36 and human platelet CD36.},
  author={Dale E Greenwalt and K. W. K. Watt and Th. Hasler and Russell J. Howard and Satyananda Patel},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 27},
  pages={16296-9}
}
Endothelial cell CD36 (glycoprotein IV) has been purified from bovine heart tissue by detergent partitioning and immunoaffinity chromatography. Bovine CD36 differs from human CD36 in its apparent mass (85 versus 88 kDa), primary structure, and immunological cross-reactivity. Of the 18 N-terminal residues identified, 17 conformed to the human CD36 sequence. Mouse monoclonal antibodies E-1 and 8A6 defined bovine- and human-specific epitopes, respectively. Because human CD36 has been identified as… CONTINUE READING
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