Strontium ranelate increases osteoblast activity.

  title={Strontium ranelate increases osteoblast activity.},
  author={Monica Marletti Almeida and Edson Parra Nani and Lucas Novaes Teixeira and Daiane Cristina Peruzzo and J{\'u}lio C{\'e}sar Joly and Marcelo Henrique Napimoga and Elizabeth Ferreira Martinez},
  journal={Tissue & cell},
  volume={48 3},
Strontium ranelate (SR) is the first generation of a new class of medication for osteoporosis, which is capable of inducing bone formation and, to a certain extent, inhibiting bone resorption. The aim of this study was to evaluate the in vitro effects of SR on osteoblastic cell cultures. MC3TE-E1 cells were seeded in 24-well plates at a density of 2×10(4) cells/well and exposed to SR at 0.05, 0.1, and 0.5mM. The following parameters were assayed: 1) Cell proliferation by hemocytometer counting… CONTINUE READING