Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation.

@article{Marie2006StrontiumRA,
  title={Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation.},
  author={Pierre Jacques Marie},
  journal={Current opinion in rheumatology},
  year={2006},
  volume={18 Suppl 1},
  pages={S11-5}
}
The increased bone remodeling in women after menopause induces an imbalance between bone resorption and formation, leading to decreased bone mass, altered bone microarchitecture, and increased fracture risk. Current antiosteoporotic drugs decrease bone remodeling or increase bone formation. Strontium ranelate (Protelos) is a newly developed antiosteoporotic drug that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. In rat and mouse culture… CONTINUE READING

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