Strontium-induced rat egg activation.

  title={Strontium-induced rat egg activation.},
  author={Reut Tomashov-Matar and Dafna Tchetchik and Avi Eldar and Ruth Kaplan-Kraicer and Y Oron and Ruth Shalgi},
  volume={130 4},
Parthenogenetic agents that evoke cytosolic calcium concentration ([Ca2+]i) oscillations similar to those evoked by sperm, mimic fertilization more faithfully than agents that trigger a single [Ca2+]i transient. Strontium chloride (SrCl2) binds to and activates the Ca2+-binding site on the inositol 1,4,5-trisphosphate receptor and evokes [Ca2+]i oscillations. Although SrCl2 has been reported to activate mouse eggs, little is known regarding the pattern of the [Ca2+]i oscillations it evokes in… CONTINUE READING