Strontium and magnesium ions released from bioactive titanium metal promote early bone bonding in a rabbit implant model.

Abstract

We have previously developed the "alkali and heat treatment" method to confer bioactivity (bone-bonding ability) to titanium metal (Ti). As strontium (Sr) and magnesium (Mg) ions reportedly promote osteoblastic cell proliferation and differentiation and accelerate bone formation, we improved this method to induce the release of Sr (Sr-Ti) or Mg (Mg-Ti) ions… (More)
DOI: 10.1016/j.actbio.2017.09.019

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Cite this paper

@article{Okuzu2017StrontiumAM, title={Strontium and magnesium ions released from bioactive titanium metal promote early bone bonding in a rabbit implant model.}, author={Yaichiro Okuzu and Shunsuke Fujibayashi and Seiji Yamaguchi and Koji Yamamoto and Takayoshi Shimizu and Takashi Sono and Koji Goto and Bungo Otsuki and Tomiharu Matsushita and Tadashi Kokubo and Shuichi Matsuda}, journal={Acta biomaterialia}, year={2017}, volume={63}, pages={383-392} }