Strongyloides stercoralis infestation associated with septicemia due to intestinal transmural migration of bacteria

  title={Strongyloides stercoralis infestation associated with septicemia due to intestinal transmural migration of bacteria},
  author={Uday Chand Ghoshal and Ujjala Ghoshal and Manoj Jain and Arvind Kumar and Rakesh Aggarwal and Asha Misra and Archana Ayyagari and Subhash R. Naik},
  journal={Journal of Gastroenterology and Hepatology},
Abstract  Strongyloides stercoralis infestation is common in the tropics and is usually asymptomatic. Patients with immunocompromised states may develop hyperinfection and fulminant disease. It has been suggested that bacteria accompany S. stercoralis during its passage across the bowel wall, resulting in systemic sepsis. Herein is a report on a 30‐year‐old man with S. stercoralis infestation and small bowel bacterial overgrowth presenting as malabsorption syndrome. He developed extensive… 

Strongyloides stercoralis hyperinfection: a dreaded but still missed diagnosis

A 50-year-old female patient who was a chronic user of glucocorticoids and had been seeking medical attention for two months because of continuous gastrointestinal symptoms died despite an adequate antibiotic regimen, vasopressor drugs, and ventilatory support, and the autopsy revealed the unsuspected finding of S. stercoralis hyperinfection and septicemia.

Strongyloides stercoralis hyperinfection presenting as acute respiratory failure and Gram-negative sepsis in a patient with astrocytoma.

  • M. ShormanJ. Al-Tawfiq
  • Medicine
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2009

Gastric Strongyloidiasis: Report of 2 Cases and Brief Review of the Literature.

2 immunocompromised patients with disseminated infection by S. strecoralis with gastric involvement are described with emphasis on recognition of the histological findings in gastric biopsies.

Strongyloides Stercoralis Infection Presenting With Severe Malabsorption And Arthritis In An Immune Competent Host

This case is unusual because of the severity of clinical symptoms, the extent of histological damage to the duodenal mucosa and the development of arthritis after eradication of the parasite.

Strongyloides stercoralis infestation in a patient with severe ulcerative colitis.

Difficulties in diagnosis and management of Strongyloides stercoralis infestation in patients with UC are discussed and importance of early recognition and treatment of this nematode before starting immunosuppressive drugs can not be overemphasized.

Gastrointestinal strongyloidiasis in immunocompromised patients: a case report.

A 45- year-old female is reported with gastric strongyloides stercoralis infection while receiving the treatment for her underlying UC, a well-known condition predisposing individuals to various infections.

Terminal ileum resection as a trigger for Strongyloides stercoralis hyperinfection and ensuing serial sepsis in a 37-year-old patient with complicated Crohn's disease: a case report.

A case of S. stercoralis hyperinfection that triggered 3 successive episodes of sepsis caused by pathogens of the gut flora in a young patient suffering from stenotic form of Crohn's disease is presented.

Severe strongyloidiasis in corticosteroid-treated patients.

Ivermectine is the best prophylactic and therapeutic option, and thiabendazole should no longer be used, however, guidelines for the prevention and management of S. stercoralis infection in such patients have not yet been established.

Bacteroides-associated pylephlebitis in a patient with strongyloidiasis.

The first report of pylephlebitis with Bacteroides bacteremia associated with underlying Strongyloides stercoralis infection is presented and the management of septic portal vein thrombosis is reviewed.

Strongyloides stercoralis hyperinfection in a patient with rheumatoid arthritis after anti-TNF-alpha therapy.

This report reports on a 63-year-old native Filipino man with a history of rheumatoid arthritis who developed Escherichia coli sepsis, filariform larvae characteristic of S. stercoralis bronchoalveolar lavage, and adult respiratory distress syndrome 3 weeks after he presented with vague gastrointestinal symptoms.



Streptococcus bovis bacteremia and meningitis associated with Strongyloides stercoralis colitis in a patient infected with human immunodeficiency virus.

  • A. JainS. AgarwalW. El-Sadr
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 1994
This case highlights the importance of searching for larvae of S. stercoralis as part of the evaluation of the gastrointestinal tract of patients with bacteremia or meningitis due to certain enteric organisms.

Syndrome of hyperinfection with Strongyloides stercoralis.

If intestinal infection with S. stercoralis is detected and treated before immunosuppressive therapy is initiated and if a high index of suspicion for the hyperinfection syndrome is maintained while immunosuficient therapy is given, the mortality from this disease should decrease.

Persistent strongyloidiasis in an immunodeficient patient.

It was postulated that the lack of signs and symptoms of strongyloidiasis, as well as poor response to treatment, was related to the immunodeficiency state, and with low-dose, long-term interrupted courses of thiabendazole treatment, the Strongyloides infection finally seemed to be cured.

Pigmented nails and Strongyloides stercoralis infestation causing clinical worsening in a patient treated for immunoproliferative small intestinal disease: two unusual observations.

A 20-year old man with IPSID lymphoma who responded to anti-malignant chemotherapy initially, but later deteriorated due to Strongyloides stercoralis infestation, which was treated successfully with mebendazole.

Systemic Strongyloidiasis in Patients Infected with the Human Immunodeficiency Virus: A Report of 3 Cases and Review of the Literature

Systemic strongloidiasis is a rare and potentially fatal complication of late-stage HIV disease and new antihelminthic drugs seem promising and need to be evaluated in controlled studies.

Small bowel bacterial overgrowth in strongyloidiasis.

It is concluded that in strongyloidiasis there is small bowel bacterial overgrowth, and so it should be considered in the pathogenesis of some of the gastrointestinal manifestations and complications of strongyloidsiasis.