Strongyloides ransomi: proteolytic enzymes from larvae.

  title={Strongyloides ransomi: proteolytic enzymes from larvae.},
  author={M. H. Dresden and Ajay A Rege and Kenneth Darwin Murrell},
  journal={Experimental parasitology},
  volume={59 2},
The filariform larvae of Strongyloides ransomi can infect their hosts by penetration through skin. In this report, homogenates of these organisms were prepared and their proteolytic enzymes examined. Homogenates prepared in 0.2 M citrate, pH 4.0, contain two thiol-dependent proteinases with molecular weights of approximately 32,000 and 28,000. These proteinases have an acidic pH optimum and show substrate preferences and inhibitor susceptibilities similar to the vertebrate acidic cysteinyl… CONTINUE READING