Strongly binding myosin crossbridges regulate loaded shortening and power output in cardiac myocytes.

Abstract

This study investigated the possible roles of strongly binding myosin crossbridges in determining loaded shortening and power output in cardiac myocytes. Single skinned cardiac myocytes were attached between a force transducer and position motor, and shortening velocities were measured over a range of loads during varying levels of Ca(2+) activation… (More)

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