Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients.

@article{Calmy2012StrongSR,
  title={Strong serological responses and HIV RNA increase following AS03-adjuvanted pandemic immunization in HIV-infected patients.},
  author={Alexandra Calmy and Michael Bel and Alain Nguyen and Christophe Combescure and C{\'e}cile Delhumeau and Sara Meier and Sabine Yerly and Laurent Kaiser and Bernard Hirschel and C Siegrist},
  journal={HIV medicine},
  year={2012},
  volume={13 4},
  pages={207-18}
}
INTRODUCTION We aimed to determine the antibody responses and effect on viral load of the AS03-adjuvanted pandemic H1N1 vaccine in HIV-infected patients. METHOD A total of 121 HIV-infected patients and 138 healthy subjects were enrolled in a prospective, open-label study. Healthy subjects received one dose and HIV-infected patients two doses of the AS03-adjuvanted split influenza A/09/H1N1 vaccine (Pandemrix®; GlaxoSmithKline, Brentford, United Kingdom.) at an interval of 3-4 weeks. The study… CONTINUE READING
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