Strong prediction of virological response to combination therapy by IL28B gene variants rs12979860 and rs8099917 in chronic hepatitis C genotype 4.

Abstract

BACKGROUND A strong association between single nucleotide polymorphisms (SNPs) of IL28B and treatment outcomes of pegylated interferon-α (PEG IFNα) and ribavirin (RBV) has been shown in chronic hepatitis C (CHC) patients with genotype 1. AIM This study aimed to assess two SNPs of IL28B, rs12979860 and rs8099917, in predicting sustained virological… (More)
DOI: 10.1111/liv.12321

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