Strong innate immune response and cell death in chicken splenocytes infected with genotype VIId Newcastle disease virus

@inproceedings{Hu2011StrongII,
  title={Strong innate immune response and cell death in chicken splenocytes infected with genotype VIId Newcastle disease virus},
  author={Zenglei Hu and Jiao Hu and Shunling Hu and Xiaowen Liu and Xiaoquan Wang and Jie Zhu and Xiufan Liu},
  booktitle={Virology Journal},
  year={2011}
}
Genotype VIId Newcastle disease virus (NDV) isolates induce more severe damage to lymphoid tissues, especially to the spleen, when compared to virulent viruses of other genotypes. However, the biological basis of the unusual pathological changes remains largely unknown. Virus replication, cytokine gene expression profile and cell death response in chicken splenocytes infected with two genotype VIId NDV strains (JS5/05 and JS3/05), genotype IX NDV strain F48E8 and genotype IV NDV strain Herts/33… CONTINUE READING