Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires

@inproceedings{Zmasek2010StrongFP,
  title={Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires},
  author={Christian M. Zmasek and Adam Godzik},
  booktitle={Genome Biology},
  year={2010}
}
Genome size and complexity, as measured by the number of genes or protein domains, is remarkably similar in most extant eukaryotes and generally exhibits no correlation with their morphological complexity. Underlying trends in the evolution of the functional content and capabilities of different eukaryotic genomes might be hidden by simultaneous gains and losses of genes. We reconstructed the domain repertoires of putative ancestral species at major divergence points, including the last… CONTINUE READING