Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers.

@article{Stumm2013StrongEO,
  title={Strong expression of the neuronal transcription factor FOXP2 is linked to an increased risk of early PSA recurrence in ERG fusion-negative cancers.},
  author={Laura Stumm and L. C. Burkhardt and Stefan Steurer and Ronald Simon and Meike Adam and Andreas Becker and Guido Sauter and Sarah J P Minner and Thorsten Schlomm and Hueseyin Sirma and Uwe H G Michl},
  journal={Journal of clinical pathology},
  year={2013},
  volume={66 7},
  pages={563-8}
}
BACKGROUND AND AIMS Transcription factors of the forkhead box P (FOXP1-4) family have been implicated in various human cancer types before. The relevance and role of neuronal transcription factor FOXP2 in prostate cancer is unknown. METHODS A tissue microarray containing samples from more than 11 000 prostate cancers from radical prostatectomy specimens with clinical follow-up data was analysed for FOXP2 expression by immunohistochemistry. FOXP2 data were also compared with pre-existing ERG… CONTINUE READING
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