Strong associations between RFLP and protein polymorphisms for CD46

Abstract

Human CD46 (membrane cofactor protein) is a cell surface glycoprotein with cofactor activity for the factor I mediated cleavage of components C3b and C4b. Using a CD46 cDNA clone, three restriction enzymes give simple two allele restriction fragment length polymorphisms (RFLPs) in samples of over 300 Caucasians. For Pvu II, P1 with a 16.5 kilobase (kb… (More)
DOI: 10.1007/BF00215283

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@article{Wilton1992StrongAB, title={Strong associations between RFLP and protein polymorphisms for CD46}, author={Alan N. Wilton and Ricky W. Johnstone and Ian McKenzie and Damian Purcell}, journal={Immunogenetics}, year={1992}, volume={36}, pages={79-85} }