Strong association of interleukin-4 (-590 C/T) polymorphism with increased risk for oral squamous cell carcinoma in Europeans.

@article{Vairaktaris2007StrongAO,
  title={Strong association of interleukin-4 (-590 C/T) polymorphism with increased risk for oral squamous cell carcinoma in Europeans.},
  author={Eleftherios G Vairaktaris and Athanasios Yannopoulos and Stavros Vassiliou and Zoe Charalambous Serefoglou and Antonis Vylliotis and Emeka Nkenke and Elena Critselis and Dimitrios Avgoustidis and Christos Yapijakis and Friedrich Wilhelm Neukam and Efstratios S. Patsouris},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2007},
  volume={104 6},
  pages={796-802}
}
OBJECTIVE The present study was performed to investigate the possible association of -590 C/T polymorphism in the interleukin-4 (IL-4) gene which affects its expression with the risk for development of oral cancer. STUDY DESIGN Polymerase chain reaction-based restriction analysis was performed in DNA samples of 156 patients with oral squamous cell carcinoma (OSCC) and 162 healthy control subjects of equivalent gender, age, and ethnicity (Greek and German). Statistical analyses were performed… CONTINUE READING
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