Strong association of autoantibodies to human nuclear lamin B1 with lupus anticoagulant antibodies in systemic lupus erythematosus.

@article{Senecal1999StrongAO,
  title={Strong association of autoantibodies to human nuclear lamin B1 with lupus anticoagulant antibodies in systemic lupus erythematosus.},
  author={J. L. Senecal and Joyce Rauch and Tamara Grodzicky and Jacques Raynauld and Imad W. Uthman and Arnulfo Nava and M Guimond and Yves Raymond},
  journal={Arthritis and rheumatism},
  year={1999},
  volume={42 7},
  pages={1347-53}
}
OBJECTIVE To determine the frequency and clinical significance of high titers of IgG autoantibodies to nuclear lamin B1 in a large number of unselected and well-characterized systemic lupus erythematosus (SLE) patients, disease controls, and normal healthy controls. METHODS A cross-sectional study of anti-lamin B1 autoantibodies, as measured by enzyme-linked immunosorbent assay using human recombinant lamin B1 autoantigen, was performed on serum samples obtained at first evaluation of 238… CONTINUE READING
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