Strong association between polymorphisms in ANKH locus and skeletal size traits

@article{Malkin2006StrongAB,
  title={Strong association between polymorphisms in ANKH locus and skeletal size traits},
  author={I. Malkin and S. Ermakov and E. Kobyliansky and G. Livshits},
  journal={Human Genetics},
  year={2006},
  volume={120},
  pages={42-51}
}
Loss of bone strength is the main determinant of bone fragility. Bone strength is directly dependent on bone size (BS). A substantial portion of BS variation is attributable to genetic effects. However, the list of genes and allelic variants involved in the determination of BS variation is far from being complete. Polymorphisms in the ANKH gene have been shown to be associated with radiographic hand BS-related phenotypes. The present study examined the possible association of the ANKH gene with… Expand
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