Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules.

Abstract

Breaking good: The amide bond is widely recognized as the strongest bond among the carboxylic acid derivatives. Therefore, the potential of amides to serve as synthetic building blocks has remained mostly untapped thus far. This Highlight describes a recent breakthrough that enables the catalytic conversion of amides into esters for the first time.

DOI: 10.1002/anie.201508536

Cite this paper

@article{Ruider2015StrongBM, title={Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules.}, author={Stefan A Ruider and Nuno Maulide}, journal={Angewandte Chemie}, year={2015}, volume={54 47}, pages={13856-8} }