Strong Association between Two Polymorphisms on 15q25.1 and Lung Cancer Risk: A Meta-Analysis

@inproceedings{Gu2012StrongAB,
  title={Strong Association between Two Polymorphisms on 15q25.1 and Lung Cancer Risk: A Meta-Analysis},
  author={Mingliang Gu and Xiaoqun Dong and Xuezhi Zhang and Xumin Wang and Yue Qi and Jun Yu and Wenquan Niu},
  booktitle={PloS one},
  year={2012}
}
BACKGROUND The association between polymorphisms on 15q25.1 and lung cancer has been widely evaluated; however, the studies have yielded contradictory results. We sought to investigate this inconsistency by performing a comprehensive meta-analysis on two polymorphisms (CHRNA3 gene: rs1051730 and AGPHD1 gene: rs8034191) on 15q25.1. METHODS Data were extracted from 15 and 14 studies on polymorphisms rs1051730 and rs8034191 involving 12301/14000 and 14075/12873 lung cancer cases/controls… CONTINUE READING

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